Article
Effects of genetic correction on the differentiation of hair cell-like cells from iPSCs with MYO15A mutation.
Cell death and differentiation - 1 Aug 2016
Chen J-R, Tang Z-H, Zheng J, Shi H-S, Ding J, Qian X-D, Zhang C, Chen J-L, Wang C-C, Li L, Chen J-Z, Yin S-K, Shao J-Z, Huang T-S, Chen P, Guan M-X, Wang J-F
Abstract excerpt
Deafness or hearing loss is a major issue in human health. Inner ear hair cells are the main sensory receptors responsible for hearing. Defects in hair cells are one of the major causes of deafness. A combination of induced pluripotent stem cell (iPSC) technology with genome-editing technology may provide an attractive cell-based strategy to regenerate hair cells and treat hereditary deafness in humans. Here, we...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.