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Effects of Freeze–Thawing and Intravenous Infusion on Mesenchymal Stromal Cell Gene Expression

25 Feb 2016

Abstract excerpt

Mesenchymal stromal cells (MSC) are increasingly used as an investigative therapeutic product for immune disorders and degenerative disease. Typically, MSC are isolated from human tissue, expanded in culture, and cryopreserved until usage. The safety and efficacy of MSC therapy will depend on the phenotypical and functional characteristics of MSC. The freeze-thawing procedure may change these characteristics....

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PMID: 26914168
DOI: 10.1089/scd.2015.0329

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