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Article

HMGB1 Facilitated Macrophage Reprogramming towards a Proinflammatory M1-like Phenotype in Experimental Autoimmune Myocarditis Development.

Scientific reports - 22 Feb 2016

Su Zhaoliang, Zhang Pan, Yu Ying, Lu Hongxiang, Liu Yanfang, Ni Ping, Su Xiaolian, Wang Dan, Liu Yueqin, Wang Jia, Shen Huiling, Xu Wenlin, Xu Huaxi

Abstract excerpt

Macrophages can be reprogramming, such as the classical activated macrophage, M1 or alternative activated macrophages, M2 phenotype following the milieu danger signals, especially inflammatory factors. Macrophage reprogramming is now considered as a key determinant of disease development and/or regression. Experimental autoimmune myocarditis (EAM) is characterized by monocytes/macrophage infiltration, Th17 cells...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26899795
DOI: 10.1038/srep21884
PMCID: PMC4761996

Genes

HMGB1
TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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