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Article

Familial Mutations and Post-translational Modifications of UCH-L1 in Parkinson's Disease and Neurodegenerative Disorders.

Current protein & peptide science - 1 Jan 2017

Lee Yun-Tzai C, Hsu Shang-Te D

Abstract excerpt

Parkinson's disease (PD) is one of the most common progressive neurodegenerative disorders in modern society. The disease involves many genetic risk factors as well as a sporadic pathogenesis that is age- and environment-dependent. Of particular interest is the formation of intra-neural fibrillar aggregates, namely Lewy bodies (LBs), the histological hallmark of PD, which results from aberrant protein homeostasis...

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Identifiers

PMID: 26899237
DOI: 10.2174/1389203717666160217143721

Genes

UCHL1

Variants

Provenance

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Familial Mutations and Post-translational Modifications of UCH-L1 in Parkinson's Disease and Neurodegenerative Disorders.PMID 26899237Read ↗

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