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Article

Sudden cardiac death in young adults: environmental risk factors and genetic aspects of premature atherosclerosis.

Journal of forensic sciences - 1 May 2012

Larsen Maiken K, Nissen Peter H, Kristensen Ingrid B, Jensen Henrik K, Banner Jytte

Abstract excerpt

Familial hypercholesterolemia (FH) is a genetic disorder that may lead to premature coronary heart disease (CHD) and sudden cardiac death (SCD). Mutations in the LDLR or APOB genes cause FH. We have screened the LDLR and the ligand-binding region of APOB genes in 52 cases of SCD. Deceased patients were younger than 40 years of age and were suspected of having FH. The LDLR and APOB genes were examined via PCR,...

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Source

Identifiers

PMID: 22220933
DOI: 10.1111/j.1556-4029.2011.02028.x

Genes

LDLR
APOB
SCD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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