Article
High prevalence of major cardiovascular risk factors in first-degree relatives of individuals with familial premature coronary artery disease--the GENECARD project.
Atherosclerosis - 1 Sept 2007
Hurrell Claire, Wietlisbach Vincent, Jotterand Valerie, Volet Marianne, Lenain Vincent, Nicod Pascal, Darioli Roger, Paccaud Fred, Waeber Gerard, Mooser Vincent
Abstract excerpt
BACKGROUND: Hypertension, hypercholesterolemia, obesity and smoking are highly prevalent among patients with familial premature coronary artery disease (FP-CAD). Whether these risk factors equally affect other family members remains unknown. METHODS: We examined 222 FP-CAD patients, 158 unaffected sibs, 197 offspring and 94 spouses in 108 FP-CAD families (> or = 2 sibs having survived CAD diagnosed before age 51...
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