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Article

Strategies in early clinical development for the treatment of basic defects of cystic fibrosis.

Expert opinion on investigational drugs - 1 Jan 2016

Dhooghe Barbara, Haaf Jérémy Boris, Noel Sabrina, Leal Teresinha

Abstract excerpt

INTRODUCTION: Twenty-six years after the identification of the gene responsible for cystic fibrosis (CF), controversies still surround the pathogenesis of the disease that continues to burden and shorten lives. Therefore, finding effective therapeutic strategies that target the basic defect of CF is crucially needed. AREAS COVERED: This review offers a comprehensive survey of fundamental therapies in early stages...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26878157
DOI: 10.1517/13543784.2016.1154041

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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