Article
A domestication related mutation in the thyroid stimulating hormone receptor gene (TSHR) modulates photoperiodic response and reproduction in chickens.
General and comparative endocrinology - 1 Mar 2016
Karlsson Anna-Carin, Fallahshahroudi Amir, Johnsen Hanna, Hagenblad Jenny, Wright Dominic, Andersson Leif, Jensen Per
Abstract excerpt
The thyroid stimulating hormone receptor gene (TSHR) has been suggested to be a "domestication locus" in the chicken. A strong selective sweep over TSHR in domestic breeds together with significant effects of a mutation in the gene on several domestication related traits, indicate that the gene has been important for chicken domestication. TSHR plays a key role in the signal transduction of seasonal reproduction,...
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