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A Rapid and Low-Cost PCR Thermal Cycler for Infectious Disease Diagnostics

12 Feb 2016

Abstract excerpt

The ability to make rapid diagnosis of infectious diseases broadly available in a portable, low-cost format would mark a great step forward in global health. Many molecular diagnostic assays are developed based on using thermal cyclers to carry out polymerase chain reaction (PCR) and reverse-transcription PCR for DNA and RNA amplification and detection, respectively. Unfortunately, most commercial thermal cyclers...

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PMID: 26872358
DOI: 10.1371/journal.pone.0149150

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