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Article

Evaluation of an oral telomerase activator for early age-related macular degeneration - a pilot study

1 Jan 2016

Abstract excerpt

PURPOSE: Telomere attrition and corresponding cellular senescence of the retinal pigment epithelium contribute to the changes of age-related macular degeneration. Activation of the enzyme telomerase can add telomeric DNA to retinal pigment epithelium chromosomal ends and has been proposed as a treatment for age-related macular degeneration. We report the use of a small molecule, oral telomerase activator (TA)-65...

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Share to Neutrophil, Myeloperoxidase and Oxidative Mechanisms
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PMID: 26869760
DOI: 10.2147/opth.s100042

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