Vitamin D Receptor Gene<i>Taq</i>I,<i>Bsm</i>I and<i>Fok</i>I Polymorphisms in Korean Patients with Tuberculosis

Abstract excerpt

BACKGROUND: The active metabolite (1, 25-dihydroxycholecalciferol) of vitamin D (25-hydroxycholecalciferol) leads to activation of macrophages and deficiency of vitamin D seems to be involved in the risk of tuberculosis. The effects of vitamin D are exerted by interaction with the vitamin D receptor (VDR) and may be influenced by polymorphism in the VDR gene. In this study, variation in the VDR gene was...

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