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Article

Induction of virulence factors in Giardia duodenalis independent of host attachment.

Scientific reports - 12 Feb 2016

Emery Samantha J, Mirzaei Mehdi, Vuong Daniel, Pascovici Dana, Chick Joel M, Lacey Ernest, Haynes Paul A

Abstract excerpt

Giardia duodenalis is responsible for the majority of parasitic gastroenteritis in humans worldwide. Host-parasite interaction models in vitro provide insights into disease and virulence and help us to understand pathogenesis. Using HT-29 intestinal epithelial cells (IEC) as a model we have demonstrated that initial sensitisation by host secretions reduces proclivity for trophozoite attachment, while inducing...

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Identifiers

PMID: 26867958
DOI: 10.1038/srep20765
PMCID: PMC4751611

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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