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Article

Giardia secretome highlights secreted tenascins as a key component of pathogenesis.

GigaScience - 1 Mar 2018

Dubourg Audrey, Xia Dong, Winpenny John P, Al Naimi Suha, Bouzid Maha, Sexton Darren W, Wastling Jonathan M, Hunter Paul R, Tyler Kevin M

Abstract excerpt

Background: Giardia is a protozoan parasite of public health relevance that causes gastroenteritis in a wide range of hosts. Two genetically distinct lineages (assemblages A and B) are responsible for the human disease. Although it is clear that differences in virulence occur, the pathogenesis and virulence of Giardia remain poorly understood. Results: The genome of Giardia is believed to contain open reading...

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Identifiers

PMID: 29385462
DOI: 10.1093/gigascience/giy003
PMCID: PMC5887430

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