Article
Sequence diversity and ligand-induced structural rearrangements of viper hyaluronidase.
Molecular bioSystems - 1 Apr 2016
Bharathi A Christian, Yadav Pradeep Kumar, Syed Ibrahim B
Abstract excerpt
Hyaluronidases (Hyals) are a class of carbohydrate-active enzyme involved in angiogenesis, cancer proliferation, tumour growth and venom spreading. Functionally significant Hyals are responsible for the fast spreading of venom to the target site of action. The absence of molecular diversity and the structural and functional behaviour of snake venom Hyals was the inspiration for the objective of this study. Echis...
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