Article
KDR gene polymorphisms and idiopathic recurrent spontaneous abortion.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians - 1 Nov 2016
Honarvar Negar, Sheikhha Mohammad Hasan, Farashahi Yazd Ehsan, Pashaiefar Hossein, Mohtaram Shirin, Sazegari Ali, Feizollahi Zahra, Ghasemi Nasrin
Abstract excerpt
OBJECTIVE: Process of angiogenesis is essential for successful gestation. Disruption in this pathway leads to various undesirable consequences in pregnancy such as recurrent spontaneous abortion (RSA). One of the most important genes involved in angiogenesis is kinase-insert domain-containing receptor (KDR). This study aimed to investigate the associations between two single-nucleotide polymorphisms (SNPs) of KDR...
Topics
- Abortion, Habitual
- Adult
- Case-Control Studies
- Female
- Gene Frequency
- Genetic Markers
- Genetic Predisposition to Disease
- Genotype
- Genotyping Techniques
- Humans
- Iran
- Odds Ratio