Article
Structure-function studies of HNF1A (MODY3) gene mutations in South Indian patients with monogenic diabetes.
Clinical genetics - 1 Dec 2016
Balamurugan K, Bjørkhaug L, Mahajan S, Kanthimathi S, Njølstad P R, Srinivasan N, Mohan V, Radha V
Abstract excerpt
Maturity-onset diabetes of the young (MODY) is a genetically heterogeneous monogenic form of diabetes characterized by onset of diabetes below 25 years of age, autosomal dominant mode of inheritance and primary defect in insulin secretion. Mutations in the gene (HNF1A) encoding transcription factor hepatocyte nuclear factor 1A (HNF-1A) results in one of the most common forms of MODY (MODY3). HNF-1A is mainly...
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