Article
Parvovirus B19 Replication and Expression in Differentiating Erythroid Progenitor Cells.
PloS one - 1 Jan 2016
Bua Gloria, Manaresi Elisabetta, Bonvicini Francesca, Gallinella Giorgio
Abstract excerpt
The pathogenic Parvovirus B19 (B19V) is characterized by a strict adaptation to erythroid progenitor cells (EPCs), a heterogeneous population of differentiating cells with diverse phenotypic and functional properties. In our work, we studied the dynamics of B19V infection in EPCs in dependence on the cell differentiation stage, in terms of distribution of infected cells, synthesis of viral nucleic acids and...
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