Article
Human Parvovirus B19 Utilizes Cellular DNA Replication Machinery for Viral DNA Replication
13 Dec 2017
Abstract excerpt
ABSTRACT Human parvovirus B19 (B19V) infection of human erythroid progenitor cells (EPCs) induces a DNA damage response and cell cycle arrest at late S phase, which facilitates viral DNA replication. However, it is not clear exactly which cellular factors are employed by this single-stranded DNA virus. Here, we used microarrays to systematically analyze the dynamic transcriptome of EPCs infected with B19V. We...
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