Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gene Therapy Strategies for Alzheimer's Disease: An Overview

1 Feb 2016

Abstract excerpt

Key neuropathological hallmarks of Alzheimer's disease (AD) are extracellular amyloid plaques and intracellular accumulation of hyperphosphorylated Tau protein. The mechanisms underlying these neuropathological changes remain unclear. So far, research on AD therapy has had limited success in terms of symptomatic treatments although it has also had several failures for disease-modifying drugs. Gene transfer...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Cholinesterase and Neurodegenerative Diseases
Share to Nuclear Receptors and Signaling

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26838997
DOI: 10.1089/hum.2016.017

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gene Therapy Strategies for Alzheimer's Disease: An OverviewPMID 26838997Read ↗

A review of the advances, insights, and prospects of gene therapy for Alzheimer’s disease: A novel target for therapeutic medicineSemantic proximity Read ↗

Targeting Alzheimer's disease with gene and cell therapiesSemantic proximity Read ↗

Strategies to alter the progression of Alzheimer's disease.Semantic proximity Read ↗

Molecular Therapeutics in Development to Treat Alzheimer’s DiseaseSemantic proximity Read ↗

Gene therapy for neurodegenerative diseasesSemantic proximity Read ↗

Stem cell‐ and gene‐based therapies as potential candidates in Alzheimer's therapySemantic proximity Read ↗

Transgenic models of Alzheimer's disease: Better utilization of existing models through viral transgenesisSemantic proximity Read ↗

Gene therapy for neurological disordersSemantic proximity Read ↗

Gene-based therapies for neurodegenerative diseasesSemantic proximity Read ↗

Significance of gene therapy in neurodegenerative diseasesSemantic proximity Read ↗

Translating cell biology into therapeutic advances in Alzheimer's disease.Semantic proximity Read ↗

Endogenous recapitulation of Alzheimer’s disease neuropathology through human 3D direct neuronal reprogrammingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.