Article
Strategies to alter the progression of Alzheimer's disease.
Current opinion in biotechnology - 1 Dec 1996
Siman R, Scott R W
Abstract excerpt
Recent advances in the genetics of familial Alzheimer's disease provide direction for therapeutic strategies to alter the progressive neurodegeneration. The rationale is particularly strong for targeting the deposition of amyloid into neuritic plaques, but attention has also turned to abnormalities in apoptosis and signal-transduction processes.
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