Article
CYP1A1 MspI Polymorphism and Cervical Carcinoma Risk in the Multi-Ethnic Population of Malaysia: a Case-Control Study.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2016
Tan Yee Hock, Sidik Shiran Mohd, Syed Husain Sharifah Noor Akmal, Lye Munn Sann, Chong Pei Pei
Abstract excerpt
BACKGROUND: Tobacco smoking is considered a risk factor for cervical cancer development due to the presence of tobacco based carcinogenic metabolites in cervical cells of female smokers. In this study, we investigated the role of the T3801C (MspI) polymorphism of CYP1A1, a gene encoding an enzyme necessary for the initiation of tobacco based carcinogen metabolism, on cervical cancer risk. The T to C substitution...
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