Article
Normal Amplitude of Electroretinography and Visual Evoked Potential Responses in AβPP/PS1 Mice.
Journal of Alzheimer's disease : JAD - 1 Jan 2016
Leinonen Henri, Lipponen Arto, Gurevicius Kestutis, Tanila Heikki
Abstract excerpt
Alzheimer's disease has been shown to affect vision in human patients and animal models. This may pose the risk of bias in behavior studies and therefore requires comprehensive investigation. We recorded electroretinography (ERG) under isoflurane anesthesia and visual evoked potentials (VEP) in awake amyloid expressing AβPPswe/PS1dE9 (AβPP/PS1) and wild-type littermate mice at a symptomatic age. The VEPs in...
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