Article
Antibiotic-tolerant Staphylococcus aureus Biofilm Persists on Arthroplasty Materials.
Clinical orthopaedics and related research - 1 Jul 2016
Urish Kenneth L, DeMuth Peter W, Kwan Brian W, Craft David W, Ma Dongzhu, Haider Hani, Tuan Rocky S, Wood Thomas K, Davis Charles M
Abstract excerpt
BACKGROUND: The continued presence of biofilm may be one cause of the high risk of failure observed with irrigation and débridement with component retention in acute periprosthetic joint infection (PJI). There is a poor understanding of the role of biofilm antibiotic tolerance in PJI. QUESTIONS/PURPOSES: (1) Do increasing doses of cefazolin result in decreased viable biofilm mass on arthroplasty materials? (2) Is...
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