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Article

The role of small-colony variants in failure to diagnose and treat biofilm infections in orthopedics.

Acta orthopaedica - 1 Jun 2007

Neut Daniëlle, van der Mei Henny C, Bulstra Sjoerd K, Busscher Henk J

Abstract excerpt

Biomaterial-related infection of joint replacements is the second most common cause of implant failure, with serious consequences. Chronically infected replacements cannot be treated without removal of the implant, as the biofilm mode of growth protects the bacteria against antibiotics. This review discusses biofilm formation on joint replacements and the important clinical phenomenon of small-colony variants...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17611841
DOI: 10.1080/17453670710013843

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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