Article
Distinctive origin of artemisinin-resistant Plasmodium falciparum on the China-Myanmar border.
Scientific reports - 2 Feb 2016
Ye Run, Hu Dongwei, Zhang Yilong, Huang Yufu, Sun Xiaodong, Wang Jian, Chen Xuedi, Zhou Hongning, Zhang Dongmei, Mungthin Mathirut, Pan Weiqing
Abstract excerpt
The artemisinin (ART), discovered in China, has been widely used against malaria in China over the last 30 years. Understanding the emergence and origin of ART resistance in China is therefore of great interest. We analyzed 111 culture-adapted isolates of P. falciparum from China-Myanmar (CM) border for their susceptibility to dihydroartemisinin using the ring stage survival assay (RSA0-3h) and genotyped their...
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