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Article

Multigenerational Inheritance of Long QT Syndrome Type 2 in a Japanese Family.

Internal medicine (Tokyo, Japan) - 1 Jan 2016

Ichikawa Mari, Ohno Seiko, Fujii Yusuke, Ozawa Junichi, Sonoda Keiko, Fukuyama Megumi, Kato Koichi, Kimura Hiromi, Itoh Hideki, Hayashi Hideki, Horie Minoru

Abstract excerpt

Congenital long QT syndrome (LQTS) is an important cause of sudden cardiac death in young people without any other structural disease. Mutations in the genes encoding the cardiac ion channels or associated proteins have been shown to result in ion channel dysfunction and thereby causing LQTS. We investigated a Japanese family with LQTS for four generations, with the female family members showing severe symptoms....

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Source

Identifiers

PMID: 26831020
DOI: 10.2169/internalmedicine.55.6014

Genes

KCNH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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