Article
Daclatasvir, sofosbuvir, and ribavirin for hepatitis C virus genotype 3 and advanced liver disease: A randomized phase III study (ALLY-3+).
Hepatology (Baltimore, Md.) - 1 May 2016
Leroy Vincent, Angus Peter, Bronowicki Jean-Pierre, Dore Gregory J, Hezode Christophe, Pianko Stephen, Pol Stanislas, Stuart Katherine, Tse Edmund, McPhee Fiona, Bhore Rafia, Jimenez-Exposito Maria Jesus, Thompson Alexander J
Abstract excerpt
UNLABELLED: Patients with hepatitis C virus (HCV) genotype 3 infection, especially those with advanced liver disease, are a challenging population in urgent need of optimally effective therapies. The combination of daclatasvir (DCV; pangenotypic nonstructural protein 5A inhibitor) and sofosbuvir (SOF; nucleotide nonstructural protein 5B inhibitor) for 12 weeks previously showed high efficacy (96%) in noncirrhotic...
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