Article
Ledipasvir-Sofosbuvir Plus Ribavirin in Treatment-Naive Patients With Hepatitis C Virus Genotype 3 Infection: An Open-Label Study.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 1 Jul 2017
Feld Jordan J, Ramji Alnoor, Shafran Stephen D, Willems Bernard, Marotta Paul, Huchet Emmanuelle, Vachon Marie-Louise, Svarovskaia Evguenia S, Huang K C, Hyland Robert H, Yun Chohee, Massetto Benedetta, Brainard Diana M, McHutchison John G, Tam Edward, Bailey Robert, Cooper Curtis, Yoshida Eric M, Greenbloom Susan, Elkhashab Magdy, Borgia Sergio, Swain Mark G
Abstract excerpt
BACKGROUND: Patients chronically infected with genotype 3 hepatitis C virus (HCV) have faster disease progression and are less responsive to current direct-acting antiviral regimens than patients infected with other genotypes. We conducted an open-label trial to evaluate the safety, tolerability, and efficacy of ledipasvir and sofosbuvir plus ribavirin in patients with genotype 3 HCV infection. METHODS: We...
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