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Article

A Cross-Disorder Method to Identify Novel Candidate Genes for Developmental Brain Disorders.

JAMA psychiatry - 1 Mar 2016

Gonzalez-Mantilla Andrea J, Moreno-De-Luca Andres, Ledbetter David H, Martin Christa Lese

Abstract excerpt

IMPORTANCE: Developmental brain disorders are a group of clinically and genetically heterogeneous disorders characterized by high heritability. Specific highly penetrant genetic causes can often be shared by a subset of individuals with different phenotypic features, and recent advances in genome sequencing have allowed the rapid and cost-effective identification of many of these pathogenic variants. OBJECTIVES:...

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Identifiers

PMID: 26817790
DOI: 10.1001/jamapsychiatry.2015.2692
PMCID: PMC5333489

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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