Article
Microevolution of Outbreak-Associated Middle East Respiratory Syndrome Coronavirus, South Korea, 2015.
Emerging infectious diseases - 1 Feb 2016
Seong Moon-Woo, Kim So Yeon, Corman Victor Max, Kim Taek Soo, Cho Sung Im, Kim Man Jin, Lee Seung Jun, Lee Jee-Soo, Seo Soo Hyun, Ahn Ji Soo, Yu Byeong Su, Park Nare, Oh Myoung-don, Park Wan Beom, Lee Ji Yeon, Kim Gayeon, Joh Joon Sung, Jeong Ina, Kim Eui Chong, Drosten Christian, Park Sung Sup
Abstract excerpt
During the 2015 Middle East respiratory syndrome coronavirus outbreak in South Korea, we sequenced full viral genomes of strains isolated from 4 patients early and late during infection. Patients represented at least 4 generations of transmission. We found no evidence of changes in the evolutionary rate and no reason to suspect adaptive changes in viral proteins.
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