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Article

Molecular Epidemiology of Ampicillin-resistant Haemophilus influenzae Causing Acute Otitis Media in Japanese Infants and Young Children.

The Pediatric infectious disease journal - 1 May 2016

Kakuta Risako, Yano Hisakazu, Hidaka Hiroshi, Kanamori Hajime, Endo Shiro, Ichimura Sadahiro, Ogawa Miho, Shimojima Masahiro, Ozawa Daiki, Inomata Shinya, Tanouchi Ayako, Kaku Mitsuo, Katori Yukio

Abstract excerpt

BACKGROUND: Nontypeable Haemophilus influenzae is a particularly important cause of acute otitis media (AOM). There is a high prevalence of β-lactamase-nonproducing ampicillin-resistant (BLNAR) strains in Japanese children, which is associated with recurrent AOM and prolonged treatment. The aim of this study was to investigate the antimicrobial susceptibility profile, mechanisms of ampicillin resistance and...

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PMID: 26808724
DOI: 10.1097/INF.0000000000001066

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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