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Clinical and Bacteriologic Analysis of Nontypeable Haemophilus influenzae Strains Isolated from Children with Invasive Diseases in Japan from 2008 to 2015.

Journal of clinical microbiology - 1 Jul 2018

Naito Sachiko, Takeuchi Noriko, Ohkusu Misako, Takahashi-Nakaguchi Azusa, Takahashi Hiroki, Imuta Naoko, Nishi Junichiro, Shibayama Keigo, Matsuoka Mayumi, Sasaki Yuko, Ishiwada Naruhiko

Abstract excerpt

Haemophilus influenzae type b (Hib) conjugate vaccines have led to dramatic reductions in Hib disease among young children worldwide. Nontypeable H. influenzae (NTHi) is now the major cause of invasive H. influenzae infections. We investigated the clinical characteristics of invasive NTHi diseases among children in Japan, to clarify the pathogenicity of isolated NTHi strains. The mortality rate was 10.7%, with...

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Identifiers

PMID: 29720429
DOI: 10.1128/JCM.00141-18
PMCID: PMC6018332

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