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Article

Rs895819 in MIR27A improves the predictive value of DPYD variants to identify patients at risk of severe fluoropyrimidine-associated toxicity.

International journal of cancer - 1 Jun 2016

Meulendijks Didier, Henricks Linda M, Amstutz Ursula, Froehlich Tanja K, Largiadèr Carlo R, Beijnen Jos H, de Boer Anthonius, Deenen Maarten J, Cats Annemieke, Schellens Jan H M

Abstract excerpt

The objective of this study was to determine whether genotyping of MIR27A polymorphisms rs895819A>G and rs11671784C>T can be used to improve the predictive value of DPYD variants to identify patients at risk of severe fluoropyrimidine-associated toxicity (FP-toxicity). Patients treated previously in a prospective study with fluoropyrimidine-based chemotherapy were genotyped for rs895819 and rs11671784, and DPYD...

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Source

Identifiers

PMID: 26804235
DOI: 10.1002/ijc.30014

Genes

DPYD

Variants

rs895819

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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