Article
Neuroblastoma messenger RNA is frequently detected in bone marrow at diagnosis of localised neuroblastoma patients.
European journal of cancer (Oxford, England : 1990) - 1 Feb 2016
van Wezel Esther M, Decarolis Boris, Stutterheim Janine, Zappeij-Kannegieter Lily, Berthold Frank, Schumacher-Kuckelkorn Roswitha, Simon Thorsten, Fiocco Marta, van Noesel Max M, Caron Huib N, van der Schoot C Ellen, Hero Barbara, Tytgat Godelieve A M
Abstract excerpt
INTRODUCTION: The clinical importance of the detection of neuroblastoma messenger RNA (mRNA) in bone marrow (BM) of localised neuroblastoma patients at diagnosis remains unclear. In this prospective multicentre study, BM samples of a large cohort, were studied using real-time quantitative polymerase chain reaction (qPCR). METHODS: BM samples at diagnosis from 160 patients with localised neuroblastoma were...
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