Article
High risk of development of renal cell tumor in end-stage kidney disease: the role of microenvironment.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jul 2016
Nagy Anetta, Walter Eva, Zubakov Dmitry, Kovacs Gyula
Abstract excerpt
End-stage renal disease (ESRD) and acquired cystic renal disease (ACRD) are associated with high risk of development of renal cell tumors (RCT) displaying unusual phenotype and genotype. The underlying molecular mechanism is not yet known. To explore the molecular microenvironment, we have established the expression profile of ESRD/ACRD kidneys. RNA extracted from normal and ESRD/ACRD kidneys and distinct types...
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