Article
Distribution of FcγR gene polymorphisms among two sympatric populations in Mali: differing allele frequencies, associations with malariometric indices and implications for genetic susceptibility to malaria.
Malaria journal - 19 Jan 2016
Cherif Mariama, Amoako-Sakyi Daniel, Dolo Amagana, Pearson Jan-Olov, Gyan Ben, Obiri-Yeboah Dorcas, Nebie Issa, Sirima Sodiomon B, Doumbo Ogobara, Troye-Blomberg Marita, Bakary Maiga
Abstract excerpt
BACKGROUND: Genetic polymorphisms in the complex gene cluster encoding human Fc-gamma receptors (FcγRs) may influence malaria susceptibility and pathogenesis. Studying genetic susceptibility to malaria is ideal among sympatric populations because the distribution of polymorphic genes among such populations can help in the identification malaria candidate genes. This study determined the distribution of three...
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