Article
Limited benefit of hepatitis B immunoglobulin prophylaxis in children of hepatitis B e antigen-negative mothers.
Singapore medical journal - 1 Oct 2016
Lee Le Ye, Aw Marion M, Saw Sharon, Rauff Mary, Tong Pearl Ys, Lee Guan Huei
Abstract excerpt
INTRODUCTION: In 2006, Singapore adopted the universal hepatitis B immunoglobulin (HBIg) policy. Since then, all infants of hepatitis B surface antigen (HBsAg)-positive mothers receive HBIg, irrespective of maternal hepatitis B e antigen (HBeAg) status. However, the benefits of HBIg for infants of HBeAg-negative mothers are unclear. We compared the vertical transmission rates among children of HBeAg-negative...
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