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Genetic regulation of methylation in human endometrium and blood and gene targets for reproductive diseases

14 Mar 2019

Abstract excerpt

Major challenges in understanding the functional consequences of genetic risk factors for human disease are which tissues and cell types are affected and the limited availability of suitable tissue. The aim of this study was to evaluate tissue-specific genotype-epigenetic characteristics in DNA samples from both endometrium and blood collected from women at different stages of the menstrual cycle and relate...

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PMID: 30871624
DOI: 10.1186/s13148-019-0648-7

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