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Geographic variation in human papillomavirus–related oropharyngeal cancer: Data from 4 multinational randomized trials

8 Jan 2016

Abstract excerpt

BACKGROUND: There are variations in the proportions of head and neck cancers caused by the human papillomavirus (HPV) between countries and regions. It is unclear if these are true variations or due to different study designs and assays. METHODS: We tested formalin-fixed paraffin-embedded diagnostic biopsies for p16 immunohistochemistry and HPV-DNA (by polymerase chain reaction [PCR] and in situ hybridization...

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PMID: 26749143
DOI: 10.1002/hed.24336

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