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Article

SOX17 promoter methylation in plasma circulating tumor DNA of patients with non-small cell lung cancer

1 Jan 2016

Abstract excerpt

BACKGROUND: SOX17 belongs to the high-mobility group-box transcription factor superfamily and down-regulates the Wnt pathway. The aim of our study was to evaluate the prognostic significance of SOX17 promoter methylation in circulating tumor DNA (ctDNA) in plasma of non-small cell lung cancer (NSCLC) patients. METHODS: We examined the methylation status of SOX17 promoter in 57 operable NSCLC primary tumors and...

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PMID: 26741346
DOI: 10.1515/cclm-2015-0776

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