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The Gut Microbiome Is Altered in a Letrozole-Induced Mouse Model of Polycystic Ovary Syndrome

5 Jan 2016

Abstract excerpt

Women with polycystic ovary syndrome (PCOS) have reproductive and metabolic abnormalities that result in an increased risk of infertility, diabetes and cardiovascular disease. The large intestine contains a complex community of microorganisms (the gut microbiome) that is dysregulated in humans with obesity and type 2 diabetes. Using a letrozole-induced PCOS mouse model, we demonstrated significant...

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PMID: 26731268
DOI: 10.1371/journal.pone.0146509

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The Gut Microbiome Is Altered in a Letrozole-Induced Mouse Model of Polycystic Ovary SyndromePMID 26731268Read ↗

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