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Article

Intestinal Flora is a Key Factor in Insulin Resistance and Contributes to the Development of Polycystic Ovary Syndrome.

Endocrinology - 1 Oct 2021

Yang Yue-Lian, Zhou Wei-Wei, Wu Shan, Tang Wen-Li, Wang Zong-Wei, Zhou Zu-Yi, Li Ze-Wen, Huang Qing-Fa, He Yan, Zhou Hong-Wei

Abstract excerpt

CONTEXT: The key gut microbial biomarkers for polycystic ovarian syndrome (PCOS) and how dysbiosis causes insulin resistance and PCOS remain unclear. OBJECTIVE: To assess the characteristics of intestinal flora in PCOS and explore whether abnormal intestinal flora can affect insulin resistance and promote PCOS and whether chenodeoxycholic acid (CDCA) can activate intestinal farnesoid X receptor (FXR), improving...

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Identifiers

PMID: 34145455
DOI: 10.1210/endocr/bqab118
PMCID: PMC8375444

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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