Multiplexed color‐coded probe‐based gene expression assessment for clinical molecular diagnostics in formalin‐fixed paraffin‐embedded human renal allograft tissue

Abstract excerpt

Histopathologic diagnoses in transplantation can be improved with molecular testing. Preferably, molecular diagnostics should fit into standard-of-care workflows for transplant biopsies, that is, formalin-fixed paraffin-embedded (FFPE) processing. The NanoString(®) gene expression platform has recently been shown to work with FFPE samples. We aimed to evaluate its methodological robustness and feasibility for...

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