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Article

Multiparameter flow cytometry is instrumental to distinguish myelodysplastic syndromes from non-neoplastic cytopenias.

European journal of cancer (Oxford, England : 1990) - 1 Feb 2016

Cremers Eline M P, Westers Theresia M, Alhan Canan, Cali Claudia, Wondergem Mariëlle J, Poddighe Pino J, Ossenkoppele Gert J, van de Loosdrecht Arjan A

Abstract excerpt

Mandatory for the diagnosis of myelodysplastic syndromes (MDS) is the presence of dysplasia in >10% of cells within one or more cell lineages or presence of >15% ring sideroblasts or presence of MDS-associated cytogenetic (CG) abnormalities. Discrimination between neo-plastic and non-neoplastic causes of cytopenias can be challenging when dysplastic features by cytomorphology (CM) are minimal and CG abnormalities...

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Identifiers

PMID: 26720403
DOI: 10.1016/j.ejca.2015.11.013

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