Article
Differentiation of zebrafish spermatogonial stem cells to functional sperm in culture.
Development (Cambridge, England) - 15 Feb 2016
Kawasaki Toshihiro, Siegfried Kellee R, Sakai Noriyoshi
Abstract excerpt
Molecular dissection and chemical screening on a complex process such as spermatogenesis could be facilitated by cell culture approaches that allow easy access for experimental manipulation and live imaging of specific molecules; however, technical limitations have thus far prevented the complete reconstruction of spermatogenic events in cell culture. Here, we describe the production of functional sperm from...
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