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Production of zebrafish offspring from cultured spermatogonial stem cells

5 Mar 2012

Abstract excerpt

Germ-line stem cells have the potential to be a very powerful tool for modifying the genetic information of individual animals. As a first step to use spermatogonial stem cells (SSCs) to enable genetic modification, we here describe effective long-term culture conditions for propagating zebrafish SSCs and for the production of offspring from these cultured SSCs after their differentiation into sperm in...

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PMID: 22390480
DOI: 10.1111/j.1365-2443.2012.01589.x

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