Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Decidual vascular endothelial cells promote maternal-fetal immune tolerance by inducing regulatory T cells through canonical Notch1 signaling.

Immunology and cell biology - 1 May 2016

Yao Yanyi, Song Jieping, Wang Weipeng, Liu Nian

Abstract excerpt

Adaptation of the maternal immune response to accommodate the semiallogeneic fetus is necessary for pregnancy success. However, the mechanisms by which the fetus avoids rejection despite expression of paternal alloantigens remain incompletely understood. Regulatory T cells (Treg cells) are pivotal for maintaining immune homeostasis, preventing autoimmune disease and fetus rejection. In this study, we found that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Decidua
Share to Fetus
Share to Immune Tolerance

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Immunosuppression Therapy

Share to Isoantigens

Share to Maternal-Fetal Exchange

Share to Receptor, Notch1

Share to T-Lymphocytes, Regulatory

Source

Identifiers

PMID: 26714886
DOI: 10.1038/icb.2015.119

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Decidual vascular endothelial cells promote maternal-fetal immune tolerance by inducing regulatory T cells through canonical Notch1 signaling.PMID 26714886Read ↗

Three Types of Functional Regulatory T Cells Control T Cell Responses at the Human Maternal-Fetal InterfaceSemantic proximity Read ↗

Regulatory T Cells: New Keys for Further Unlocking the Enigma of Fetal Tolerance and Pregnancy ComplicationsSemantic proximity Read ↗

Fetomaternal Immune Tolerance: Crucial Mechanisms of Tolerance for Successful Pregnancy in HumansSemantic proximity Read ↗

Regulatory T Cells: Regulators of LifeSemantic proximity Read ↗

New Paradigm in the Role of Regulatory T Cells During PregnancySemantic proximity Read ↗

Regulatory B Cells in Pregnancy: Lessons from Autoimmunity, Graft Tolerance, and CancerSemantic proximity Read ↗

Placental endovascular extravillous trophoblasts (enEVTs) educate maternal T‐cell differentiation along the maternal‐placental circulationSemantic proximity Read ↗

A comprehensive review of the roles of T-cell immunity in preeclampsiaSemantic proximity Read ↗

Regulatory T-Cells in Pregnancy: Historical Perspective, State of the Art, and Burning QuestionsSemantic proximity Read ↗

HLA-G Orchestrates the Early Interaction of Human Trophoblasts with the Maternal NicheSemantic proximity Read ↗

Evidence for a Selective Migration of Fetus-Specific CD4+CD25bright Regulatory T Cells from the Peripheral Blood to the Decidua in Human PregnancySemantic proximity Read ↗

Mechanisms of Fetal T Cell Tolerance and Immune RegulationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.