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Article

Aggressive tumor microenvironment of solid predominant lung adenocarcinoma subtype harboring with epidermal growth factor receptor mutations.

Lung cancer (Amsterdam, Netherlands) - 1 Jan 2016

Saruwatari Koichi, Ikemura Shinnosuke, Sekihara Keigo, Kuwata Takeshi, Fujii Satoshi, Umemura Shigeki, Kirita Keisuke, Matsumoto Shingo, Yoh Kiyotaka, Niho Seiji, Ohmatsu Hironobu, Ochiai Atsushi, Kohrogi Hirotsugu, Tsuboi Masahiro, Goto Koichi, Ishii Genichiro

Abstract excerpt

INTRODUCTION: Tumor microenvironment critically affects cancer progression. This study aimed to identify differences in microenvironments of lung adenocarcinomas with epidermal growth factor receptor (EGFR) mutations by histological subtypes. METHODS: The study cohort included 214 lung adenocarcinomas harboring EGFR mutations. We analyzed clinicopathological characteristics of lepidic (LPA), papillary (PPA),...

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Identifiers

PMID: 26711928
DOI: 10.1016/j.lungcan.2015.11.012

Genes

EGFR
LPA
PDPN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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