Article
The frequency of HLA alleles in the Romanian population.
Immunogenetics - 1 Mar 2016
Constantinescu Ileana, Boșcaiu Voicu, Cianga Petru, Dinu Andrei-Antoniu, Gai Elena, Melinte Mihaela, Moise Ana
Abstract excerpt
Knowledge of human leukocyte antigen (HLA) allele frequencies is essential for bone marrow and kidney donor searches. The Romanian Caucasian population is heterogeneous and information on HLA polymorphism has not been well studied. We characterized the HLA genetic profile and allele frequencies of regional populations in Romania. HLA-A, B and DRB1 alleles were examined in 8252 individuals, belonging to the four...
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