Genetic factors moderate everyday physical activity effects on executive functions in aging: Evidence from the Victoria Longitudinal Study.

doi:10.1037/neu0000217

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Article

Genetic factors moderate everyday physical activity effects on executive functions in aging: Evidence from the Victoria Longitudinal Study.

Neuropsychology - 1 Jan 2016

Thibeau Sherilyn, McFall G Peggy, Wiebe Sandra A, Anstey Kaarin J, Dixon Roger A

Abstract excerpt

OBJECTIVE: Everyday physical activity (EPA) is an important modifiable contributor to age-related variability in executive functioning (EF). However, its role may be moderated by nonmodifiable genetic factors. We tested independent and interactive effects of brain-derived neurotrophic factor (BDNF rs6265) and insulin degrading enzyme (IDE rs6583817) on EF and EPA-EF relationships. METHOD: The sample consisted of...

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PMID: 26710092
DOI: 10.1037/neu0000217
PMCID: PMC4693634

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BDNF

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